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CBC with Differential

The CBC with Differential offers a detailed snapshot of your red and white blood cells, hemoglobin, hematocrit, and platelets — helping detect anemia, infections, immune activity, and more.

This panel looks at 14+ lab markers grouped into red blood cells, white blood cells (and their subtypes), hemoglobin-related metrics, and platelets. 

Explore the Complete Blood Count with Differential

From fatigue to fevers, your symptoms often begin in your blood. The CBC with Differential is one of the most commonly ordered blood tests — and for good reason. It helps uncover underlying conditions by analyzing the core components of your blood.

👉 Click “Read More” to dive into easy-to-understand explanations of each test — what it measures, why it matters, and how it connects to your everyday health.

Basophils
Basophils (Absolute)

Eos

Eosinophils
Eosinophils (Absolute)

Hct

Hematocrit

Hb

Hemoglobin
Immature Grans (Absolute)

IG%

Immature Granulocytes
Lymphocytes
Lymphocytes (Absolute)

MCH

Mean Corpuscular Hemoglobin
Mean Corpuscular Hemoglobin Conc.

MCV

Mean Corpuscular Volume
Monocytes
Monocytes (Absolute)
Neutrophils
Neutrophils (Absolute)

Plt

Platelet Count

RBC

Red Blood Cell Count

RDW

Red Cell Distribution Width

WBC

White Blood Cell Count

Example LabCorp Report (CBC)

Below is a redacted image of a real Complete Blood Count with Differential blood test report from Labcorp. This example helps you recognize how lab results typically appear and provides visual context as you explore what each test measures and why it matters.

Let’s Break Down the Complete Blood Count

These results show a well-balanced and healthy blood profile. Red blood cells, hemoglobin, and hematocrit are all in a healthy range, supporting strong oxygen delivery throughout your body. White blood cell counts look normal, with no signs of infection or immune stress. Platelet levels are ideal, meaning your blood is clotting properly. Everything in this panel points to a strong circulatory and immune system. Overall, this CBC appears within normal limits, with no red flags.

Some values are at the upper/lower ends of normal, which may warrant awareness but not concern without symptoms.

  • WBC (White Blood Cell Count) – Healthy immune cell levels; no sign of infection or immune activation.
  • RBC (Red Blood Cell Count) – Excellent oxygen-carrying capacity.
  • Hemoglobin – Delivers oxygen from lungs to tissues; strong and stable.
  • Hematocrit – Reflects the percentage of red blood cells in your blood; in a great range.
  • MCV (Mean Corpuscular Volume) – Indicates your red blood cells are a healthy size.
  • MCH / MCHC – Suggests good hemoglobin content in each red blood cell.
  • RDW (Red Cell Distribution Width) – Uniform red blood cell size; no signs of anemia or nutrient deficiency.
  • Platelets – Great clotting function; no concern for bleeding or clotting issues.

 

⚠️ Important Note Before You Begin

The information on this page is provided for educational purposes only and is not medical advice. Lab test results can vary from person to person and must be interpreted in the context of your full health picture — including your symptoms, medical history, and any medications you may be taking.

If you see a result outside the normal range, don’t panic — it doesn’t always mean something is wrong. Only a licensed healthcare provider can accurately interpret your labs and recommend appropriate next steps.

That said, we’ve included general health topics, lifestyle tips, and nutritional guidance that you may find helpful as a starting point for informed conversations with your doctor or registered dietitian.

What CBC with Differential Panel Tells You
— and Why It Matters

The CBC with Differential is a cornerstone test that evaluates your blood’s essential components. It can help detect:

  • Anemia (low red blood cells or hemoglobin)
  • Infections or immune response (elevated white blood cells)
  • Inflammation or chronic disease (e.g., abnormal differential counts)
  • Bone marrow disorders
    Clotting issues (through platelet counts)

 

How This Panel Connects to Your Body Systems

Every lab test tells a part of your body’s story. In this section, we break down the body systems or health topics related to each test in the panel — like kidney function, metabolism, or liver health. This helps you understand why your doctor might order these tests and how they relate to specific organs or functions.

Whether you’re monitoring a chronic condition or just trying to stay informed, this connection helps turn lab numbers into meaningful health insights. Below you can see the body system, and the lab test associated with it. 

Immune System

White blood cell counts (WBC, Neutrophils, Lymphocytes, etc.) detect infection or inflammation.

Oxygen Delivery

RBC, Hemoglobin, and Hematocrit show how well your body delivers oxygen.

Nutrient Status

Low red cell size or hemoglobin can suggest iron, B12, or folate deficiency.

Bone Marrow Health

Immature cells (like immature granulocytes) may signal issues in cell production.

Clotting Ability

Platelet count shows your body’s ability to form clots and stop bleeding.

Lifestyle & Dietary Guidance for
a Healthier Complete Blood Count

Your Complete Blood Count (CBC) provides insight into your body’s oxygen-carrying capacity, immune function, and blood clotting ability. It helps detect early signs of anemia, inflammation, infection, or other systemic issues. Below are key components of the CBC and practical tips to support healthier blood values through small, intentional changes.

 

This content is for educational purposes only and is not medical advice. Always consult your healthcare provider before making changes to your diet, lifestyle, or treatment plan.

Red Blood Cells, Hemoglobin, and Hematocrit

Lifestyle Tip:

Dietary Guidance:

White Blood Cells (Neutrophils, Lymphocytes, etc.)

Lifestyle Tip:

Dietary Guidance:

Platelets

Lifestyle Tip:

Dietary Guidance:

References - Resources

Complete Blood Count (CBC)

These trusted external resources offer additional in-depth information about the Complete Blood Count (CBC) and how to support healthy blood values through diet and lifestyle.

MedlinePlus: National Library of Medicine

Title: Complete Blood Count (CBC): Purpose, Procedure, and Results
Description:
Healthline provides a consumer-friendly breakdown of CBC components, what abnormal results may suggest, and how it connects to your overall health.
Healthline is a trusted health information site known for accurate and approachable content.
Link: https://www.healthline.com/health/complete-blood-count

National Institutes of Health (NIH) / PMC

Title: The Complete Blood Count (CBC) and White Blood Cell Differential: Reference Range, Interpretation, and Clinical Relevance
Description:
A peer-reviewed scientific article that dives deeper into how to interpret CBC and white blood cell differential results in a clinical context. Ideal for users who want to understand how lab values reflect inflammation, infection, anemia, and more.
Published in: Primary Care Companion for CNS Disorders – a medical journal archived by the NIH’s PubMed Central.
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997421/

⚠️ Health Information Disclaimer

Important: The information provided on this website is for educational and informational purposes only. It is not intended as medical advice, diagnosis, or treatment and should not be used as a substitute for professional medical care.

Always consult a qualified healthcare provider or licensed physician regarding your individual health concerns, medical conditions, or any questions you may have about lab results, symptoms, or treatments. Never delay or disregard professional advice because of something you read here.

By continuing, you acknowledge that you understand and agree to this disclaimer.